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[e-drug] Prescrire International n°154 - November 2014

E-DRUG: Prescrire International n°154 - November 2014
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PRESCRIRE INTERNATIONAL - Independent information by and for healthcare 
professionals

View complete contents:
http://english.prescrire.org/en/SummaryDetail.aspx?Issueid=154

In the November issue of Prescrire International:

* FEATURED REVIEW:
Type 2 diabetes and metformin. First choice for monotherapy: weak evidence of 
efficacy but well-known and acceptable adverse effects.
The efficacy of metformin in type 2 diabetes is still thinly documented in 
2014. However, an abundance of data is now available on its adverse effects. 
The evidence is relatively weak, but long experience with the use of metformin 
has shown that its adverse effect profile is acceptable.

http://english.prescrire.org/en/81/168/49555/0/NewsDetails.aspx

* FREE DOWNLOAD:
Artesunate - the standard intravenous treatment for severe attacks of malaria.
Plasmodium falciparum malaria can be life-threatening, particularly in young 
children, migrants, travellers and pregnant women. This sample page from the 
"New Products" section of the November issue sums up the factors that make 
intravenous artesunate the treatment of choice for severe attacks of Plasmodium 
falciparium malaria.
SUMMARY:
- Intravenous artesunate is more effective in reducing mortality than 
injectable quinine.
- It also has a better adverse effect profile and is more convenient to use.
- Full marketing authorisation in the EU would improve access to this drug.

http://english.prescrire.org/en/81/168/49556/0/NewsDetails.aspx

©Prescrire 1 November 2014

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Regards,

Bruno Toussaint
Publishing Director, Prescrire
Website: english.prescrire.org
contact@prescrire.org>
international <international@prescrire.org>

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