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[e-drug] Prescrire International n°153 - October 2014

E-DRUG: Prescrire International n°153 - October 2014
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PRESCRIRE INTERNATIONAL - Independent information by and for healthcare 
professionals

View complete contents:
http://english.prescrire.org/en/SummaryDetail.aspx?Issueid=153

In the September issue of Prescrire International:

FEATURED REVIEW:
Rivaroxaban 2.5 mg (Xarelto°): no justification for using this anticoagulant 
after an acute coronary syndrome.
It has not been demonstrated that adding rivaroxaban to aspirin alone or to 
aspirin plus clopidogrel benefits patients who have had an acute coronary 
syndrome. The risk of serious and fatal bleeds is probably underestimated. 
Caution dictates that rivaroxaban should not be added to established 
antithrombotic therapy in this setting.

http://english.prescrire.org/en/81/168/49450/0/NewsDetails.aspx

FREE DOWNLOAD:
Adverse effects of boceprevir, colchicine and fluourouracil.
In this sample page from the Adverse Effects section, haematological disorders 
with boceprevir, deaths linked to colchicine, and dosing errors with 
flourouracil.
SUMMARY:
- Boceprevir: serious haematological disorders.
Monitoring blood cell counts is essential.
- Colchicine: more deaths.
Advanced age and renal failure are risk factors.
- Fluorouracil: dosing errors with infusion pumps.
Prevention includes double-checking.

http://english.prescrire.org/en/81/168/49451/0/NewsDetails.aspx

©Prescrire 1 October 2014
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Regards,

Bruno Toussaint
Publishing Director, Prescrire
Website: english.prescrire.org
contact@prescrire.org

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