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E-DRUG: Economic applications of DDD's (cont)

E-drug:  Economic applications of DDD's (cont)
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Dear friends,

Prof.Urquhart's remark stresses the important point made earlier by our
Norwegian colleagues, that DDD is NOT equivalent to the
medically or pharmacologically optimal dose! It is a stock-taking unit and
not much more. Misunderstanding this nearly led to a major political crisis
in Holland, where it led to considerable damage to the poltical leader of
the liberal party, who protested on behalf of MSD and was then criticized
for his double role as MP and member of MSD's board of governors.
Anyhow, everybody was poorly informed because a major trial
comparing doses had been done in Nijmegen university many years
ago. Look in Medline.

Best wishes
Dr.L.Offerhaus
Koedijklaan 1a, NL-1406 KW Bussum, The Netherlands
Phoen: 0031-35-6923288  Fax: 0031-35-6923290
E-mail: LO@EURONET.NL; CompuServe 71530,15
EJCP Only: POB 75552, NL-1070AN Amsterdam



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