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E-DRUG: Drug Information

E-drug: Drug Information (2)
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Dear Josephine,

The Mogidone (sp) from Kenya is probably Mogadon (R) or nitrazepam. It is 
indeed made by
Roche in a 5 mg tablet.

I am worried about the statement that he has been taking it for years: 
benzodiazepines for
insomnia are indicated only for a maximum duration of 2 weeks. After that the 
efficacy
reduces and the risks of dependence increase. The South African Medicines 
Formulary (4th
edition, page 380) estimates that 40-50% of patients will become dependent on 
the drug
after one year of continuous treatment.

kind regards,

Wilbert Bannenberg, MD
South Africa  
Email: WilbertBannenberg@compuserve.com 
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