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[afro-nets] Male Circumcision for Reduction of HIV Infection Risk


Male Circumcision for Reduction of HIV Infection Risk
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Randomized, Controlled Intervention Trial of Male Circumcision 
for Reduction of HIV Infection Risk: The ANRS 1265 Trial
 
By Bertran Auvert, Dirk Taljaard, Emmanuel Lagarde, Joëlle Sob-
ngwi-Tambekou, Rémi Sitta and Adrian Puren
PLoS Med 2(11): e298 (October 25, 2005)
 
Adobe PDF file (11 pp. 435 kB):
http://medicine.plosjournals.org/perlserv/?request=get-pdf&file=10.1371_journal.pmed.0020298-p-S.pdf
 
Observational studies suggest that male circumcision may provide 
protection against HIV-1 infection. A randomized, controlled in-
tervention trial was conducted in a general population of South 
Africa to test this hypothesis. The authors conclude that male 
circumcision provides a degree of protection against acquiring 
HIV infection, equivalent to what a vaccine of high efficacy 
would have achieved. Male circumcision may provide an important 
way of reducing the spread of HIV infection in sub-Saharan Af-
rica.

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